By Prof. Dr. med. Heinz Grefor Wieser (auth.), B. Sutter, O. Schröttner (eds.)
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Additional resources for Advances in Epilepsy Surgery and Radiosurgery
Between 1955 and 1973, Talairach and colleagues treated 44 epileptic patients 38 by stereotactic implantation of Yttrium 90 into the amygdala and the hippocampus . Two patients in this series experienced hemiparesis due to anterior choroid artery occlusion. These technical difficulties, related to the use of the radioelement, led to subsequent abandonment of this approach, however, first clinical results were promising . A few years later Steiner and Lindquist, analyzing their clinical experience with arteriovenous malformations (AVM), noted that epilepsy was frequently improved after GK surgery [22, 35, 65, 66].
O'Brien n, So EL, Mullan BP, Cascino GD, Hauser MF, Brinkmann BH, Sharbrough FW, Meyer FB (2000) Subtraction peri-ictal SPECT is predictive of extra temporal epilepsy surgery outcome. Neurology 55: 1668-1677 59. O'Brien n, So EL, MulIan BP, Hauser MF, Brinkmann BH, Bohnen NI, Hanson D, Cascino GD, Jack CRJ, Sharbrough FW (1998) Subtraction ictal SPECT co-registered to MRI improves clinical usefulness of SPECT in localizing the surgical seizure focus. Neurology 50: 445-454 60. Olsen RW, McCabe RT, Wamsley JK (1990) GABAA receptor subtypes: autoradiographic comparison of GABA, benzodiazepine, and convulsant binding sites in the rat central nervous system.
A similar observation was made after brachytherapy , conformal radiotherapy , and conventional radiotherapy . Barcia-Salorio reported in a short abstract the antiepileptic potential of ionizing radiation in an experimental cat model of epilepsy . The same author, since 1985, has published in several proceedings interesting clinical results but till now no peer reviewed paper has been issued . Materials Gamma Knife Surgery of Mesial Temporal Lobe Epilepsy Several reasons led us to propose the evaluation of Gamma Knife Surgery in this indication.
Advances in Epilepsy Surgery and Radiosurgery by Prof. Dr. med. Heinz Grefor Wieser (auth.), B. Sutter, O. Schröttner (eds.)