The Thirteenth Step: Addiction in the Age of Brain Science by Markus Heilig PDF

By Markus Heilig

ISBN-10: 0231539029

ISBN-13: 9780231539029

The earlier twenty-five years have witnessed a revolution within the technology of habit, but we nonetheless rely on sorely superseded tools of therapy. pricey new courses for dealing with habit also are flourishing, yet considering they aren't dependent in technology, they give little gain to those that can't find the money for to lose funds or religion of their recovery.

Clarifying the state of the art technological know-how of dependancy for practitioners and common readers, The 13th Step pairs tales of genuine sufferers with reasons of key options in terms of their sickness.

A police leader who disappears at the activity illustrates the method wherein a drug can set off the mind circuits mediating relapse. One person's attempt to discover a burrito shack in a overseas urban illuminates the gift prediction errors signaled by way of the mind chemical dopamine.

With those examples and extra, this quantity paints a shiny, relatable portrait of drug looking, escalation, and different elements of dependancy and indicates science-based remedies that promise to enhance troubling relapse charges.

Merging technology and human adventure, The 13th Step deals compassionate, useful solutions to somebody who hopes for a greater deal with on a pernicious and confounding ailment.

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Extra info for The Thirteenth Step: Addiction in the Age of Brain Science

Sample text

External mentors for this development award include Drs. John March and John Curry (Duke University Medical Center). External consultants for this development award include Drs. David Brent, Maria Kovacs, Graham Emslie and Thomas Ellis. The research study described in this application is designed to examine the feasibility and efficacy of two different combinations of treatment (combined cognitive-behavioral therapy and pharmacotherapy vs. combined supportive therapy and education and pharmacotherapy) for depressed, suicidal adolescents.

Homelessness is the primary adverse outcome we hope to diminish. Other adverse outcomes include: suicidal ideation and behavior; violence toward others; and psychiatric re-hospitalization. CTI is a time-limited intervention designed specifically to enhance the continuity and focus of care during such transitions. It does not replace community treatment and supports, but instead is meant to complement available services. CTI has previously been demonstrated to be effective with severely mentally ill men following discharge from psychiatric care in a shelter institution to community care.

4) To develop new imaging modalities that are pertinent to suicide research. Over the next five years, our development effort will be targeted at the serotonin (5-HT) system with PET. The choice of these objectives is guided by a general model of neurochemical imbalance associated with suicide vulnerability provided in the background section. 1) To develop and validate a measure of 5HT/2A receptors binding potential in humans using the radiolabeled antagonist [11C],DL 100907; 2) To develop a new radiotracer to measure 5-HT/1B receptors with PET ([11C]GR127935); 3) To develop a new radiolabeled agonist to measure the agonist high affinity state of the 5HT/1A receptors ([11C]MHA) and to develop with this ligand a measure of 5-HT release based on endogenous competition techniques; 4) To develop a radiolabeled agonist to measure high affinity state of 5HT/2A receptors ([123I]/[11C]DOI).

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The Thirteenth Step: Addiction in the Age of Brain Science by Markus Heilig


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